The most common reason for this is something has changed in the web site permissions.
- Check the Application Pool Identity and/or DCOM Identity to see if it is still set to the correct account.
- Verify the Identity password. Note if the password has been changed, you will also need to update the Application Pool Identity and/or DCOM Identity credentials, then reset IIS.
- Verify that the IIS Internet User account (e.g. IIS_IUSRS on 2008/2012 servers) has the appropriate permissions.
- Verify that the ACEweb User Account has the appropriate permissions.
- If this happens after an ACEweb upgrade, verify that the wc.dll in the wconnect folder is not blocked (right-click the file, choose Properties, click the Unblock button or check the Unblock box, then click the OK button). After unblocking it, reset IIS before trying the page again.
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